Cardiovascular sciences
Our research into regenerative cardiovascular medicine ranges from direct reprogramming for cardiac fibroblasts to cardiomyocytes and the use of cardiomyocyte iPS models, to understanding the role developmental pathways play in hypertrophy and the role of specific proteins involved in channelopathies.
Our expertise
Keywords
Matthew Daniels
Matthew makes and applies genetically encoded probes to monitor cardiomyocyte function in living cells in the dish, or the whole animal. He observes cell function and survival in the early days post-delivery.
Maria Jeziorska
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Maria’s research focuses on small fibre nerve fibres and microvasculature in peripheral neuropathies in diseases such as diabetes, Parkinson’s disease and connective tissue diseases.
Valerie Kouskoff
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Research in Valerie’s group focuses on further understanding the molecular and cellular mechanisms underlying the formation of the haematopoietic system.
Georges Lacaud
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George is interested in the role of transcription factors in the development, maintenance and malignancies of the haematopoietic system. Read more on the Cancer Research UK Manchester Institute website.
Christopher Miller
Delvac Oceandy
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Delvac’s group is interested in investigating signalling pathways which can be targeted to induce cardiomyocyte regeneration.
Emmanuel Pinteaux
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Emmanuel’s research is to characterise and develop new regenerative medicine solutions (stem cell therapy, biomaterials) for the therapeutic treatment of stroke.
Tao Wang
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Using iPSC disease models, Tao studies genetic small vessel disease and neurovascular interactions, and exploring biodegradable scaffolds for stem cell in situ differentiation and vascular regeneration, and functionalising nanomaterials for biomedical applications.