Musculoskeletal
Manchester possesses substantial academic and clinical strengths in musculoskeletal research, ranging from the generation of ESC and iPS-derived chondrocytes and research into the degeneration and regeneration of intervertebral discs, to the treatment of Duchenne muscular dystrophy through novel cell therapy techniques, and the reconstruction of tendons.
Our expertise
Keywords
Sanj Anand
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Sanj specialises in cartilage regeneration, OA and ligament reconstruction.
Bilal Barkateli
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Bilal is a knee surgeon with a specialist interest in joint preservation. Bilal’s key areas of research are ligament, meniscus and cartilage regeneration.
Sarah Cartmell
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Electrical stimulation for orthopaedic and peripheral nerve tissue regeneration. Scaffold manufacture and characterisation including micro CT imaging development.
Anthony Day
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Anthony is developing a protein-based biological drug with anti-inflammatory and tissue-protective properties. He studies the role of glycosaminoglycan-protein interactions in inflammation, tissue organisation and stem cell biology.
Marco Domingos
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Marco works on the development and application of advanced 3D bioprinting platforms for regenerative medicine and tissue engineering therapies.
Julie Gough
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Professor Gough’s research encompasses controlling cell responses at the cell-biomaterial interface by engineering defined surfaces and developing scaffolds for tissue repair such as novel hydrogels and various porous and fibrous materials.
Judith Hoyland
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Judith works on the development of cell based tissue engineering and regenerative therapies for musculoskeletal tissues, specifically the intervertebral disc.
Susan Kimber
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Sue focuses on using human pluripotent stem cells for disease modelling and regenerative medicine. She is interested in human kidney and cartilage development and genetic disease.
Qing-Jun Meng
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Qing-Jun’s work focuses on 24 hour circadian rhythms and their roles in temporally regulating tissue homeostasis, repair and regeneration.
Samuel Moxon
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Samuel works on the development of hydrogel-based models of neurodegenerative diseases.
Stephen Richardson
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Dr Richardson works on adult human multipotent stem cells and their application in regenerative therapies for musculoskeletal tissues, including intervertebral disc, articular cartilage and bone.
Michael Sherratt
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Michael works on the development of new biochemical, biomechanical and biophysical approaches to characterising tissue degeneration and inducing tissue repair.
Paul Townsend
Paul’s research focuses on cartilage and chondrocyte biology and inflammation/ OA, and the role of small molecules and peptides in regenerating cartilage.
Olga Tsigkou
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Olga focuses on the combination of scaffolds with hydrogels, stem cells and 3D cell culture for tissue regeneration, predominantly bone tissue. Her group developed robust protocols for disease modelling.
Aravind Vijayaraghavan
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Aravind works on tissue scaffolds and biosensors based on graphene and related nanomaterials, understanding the fundamentals of interaction between bio-molecules and cells with nanomaterials.
Jason Wong
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Jason’s research focuses on translating soft tissue, vascular, and composite tissue bioscience towards clinical benefit of injured, wounded and traumatised patients. This includes understanding tissue scarring, complex wounds and the biomechanics of rehabilitation.